Criteria for severe cardiorespiratory failure includes:
One or more of the following for 3 - 6 hours:
  • Preductal SpO2 < 80%
  • High PaCO2 (>70 mmHg)
  • Persistent respiratory acidosis (pH < 7.2)
  • Persistent lactic acidosis ( > 3 mmol/L)
  • Refractory hypotension
  • Severe RV / LV dysfunction
OR
High ventilator pressures (HFOV: MAP ≥ 15 cm H2O or CMV: PIP ≥ 26 cm H2O) for 3-6 hours
OR
OI > 40 > 4 hours or OI > 25 > 48 hours with iNO
OR
Ventilator associated lung injury

Is there any improvement?