Treprostinil:
Intravenous pulmonary vasodilator
ECMO Dose Adjustment:
NONE
Renal Impairment Dose Adjustment:
NONE
CRRT Dose Adjustment:
NONE
Hepatic Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients.
Adult Starting Dose^:
Adult Continuous Infusion: 1.25 ng/kg/min
Pediatric Starting Dose^:
Pediatric Continuous Infusion: 1.25 ng/kg/min
Neonatal Starting Dose^:
Neonatal Continuous Infusion: 2 ng/kg/min
^Dose titration will be dependent on response and tolerability.
*Dose adjustment will be dependent on acuity and severity of impairment.