Plazomicin:
Intravenous aminoglycoside
ECMO Dose Adjustment:
No data. Expected minimal sequestration
Renal Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients. Perform therapeutic drug monitoring when available to guide dosing
CRRT Dose Adjustment:
NONE. No data exists. Perform therapeutic drug monitoring
- when available to guide dosing
Hepatic Impairment Dose Adjustment:
NONE
Adult Dose:
15 mg/kg IV every 24 hours
Pediatric Dose:
No data, choose alternate aminoglycoside
Neonatal Dose:
No data, choose alternate aminoglycoside