Minocycline:

Intravenous tetracycline derivative

ECMO Dose Adjustment:

NONE

Renal Impairment Dose Adjustment:

NONE

CRRT Dose Adjustment:

NONE

Hepatic Impairment Dose Adjustment:

NONE

Adult Dose:

200 mg IV every 12 hours

Pediatric Dose:

Do not use in children < 8 years of age unless the expected benefits of therapy outweigh the risks.

> 8 years of age: initial 4 mg/kg/dose (max 200 mg) IV, followed by 2 mg/kg/dose (max 100 mg/dose) IV every 12 hours

Neonatal Dose:

No data. Use alternate antimicrobial