Levofloxacin:
Intravenous fluoroquinolone
ECMO Dose Adjustment:
NONE
Renal Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients
CRRT Dose Adjustment:
YES—the dose may need to be increased relative to the renal impairment dose
Hepatic Impairment Dose Adjustment:
NONE
Adult Dose:
750 mg IV every 24 hours
Pediatric Dose:
6 months to < 5 years of age: 8–10 mg/kg IV every 12 hours
≥ 5 years of age: 10 mg/kg/dose IV every 24 hours; Maximum dose: 750 mg/day
Neonatal Dose:
No neonatal dosing available. Use alternate antimicrobial