Ertapenem:
Intravenous carbapenem
ECMO Dose Adjustment:
NONE. In the absence of published data, consider alternative carbapenem due to potential for sequestration based on drug characteristics alone
Renal Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients
CRRT Dose Adjustment:
YES—the dose may need to be increased relative to the renal impairment dose
Hepatic Impairment Dose Adjustment:
NONE
Adult Dose:
1 g IV daily
Pediatric Dose:
3 months to 12 years of age: 15 mg/kg IV every 12 hours (maximum 500 mg/dose and 1 g/day)
≥ 13 years of age: 1 g IV every 24 hours, (maximum 1g/day)
Neonatal Dose:
No information. Use alternative antimicrobial