Ciprofloxacin:
Intravenous fluoroquinolone
ECMO Dose Adjustment:
NONE
Renal Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients
CRRT Dose Adjustmen t:
YES—the dose may need to be increased relative to the renal impairment dose
Hepatic Impairment Dose Adjustment:
NONE
Adult Dose
400 mg IV every 8 hours
Pediatric Dose:
10 mg/kg/dose (maximum 400 mg/dose) IV every 8–12 hours
Neonatal Dose
Postmenstrual Age < 34 weeks: 7.5–10 mg/kg/dose IV every 12 hours
Postmenstrual age ≥ 34 weeks: 10–15 mg/kg/dose IV every 12 hours