Cefoxitin:
Intravenous second-generation cephalosporin
ECMO Dose Adjustment:
YES—an increased dose may be warranted in some patients
Renal Impairment Dose Adjustment*:
YES—a decreased dose may be warranted in some patients
CRRT Dose Adjustment:
YES—the dose may need to be increased relative to the renal impairment dose
Hepatic Impairment Dose Adjustment:
NONE
Adult Dose:
2 g IV every 6 hours
Pediatric Dose:
3 months of age and older: 80–160 mg/kg/day IV divided every 6-8 hours; maximum 2 g/dose, 12 g/day
Neonatal Dose:
90–100 mg/kg/day IV divided every 8 hours